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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HES3
All Species:
10.3
Human Site:
S77
Identified Species:
22.67
UniProt:
Q5TGS1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TGS1
NP_001019769.1
186
19968
S77
R
S
C
L
P
G
V
S
Q
L
L
R
R
G
D
Chimpanzee
Pan troglodytes
XP_001162588
239
25232
T81
S
E
C
M
N
E
V
T
R
F
L
S
T
C
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546749
200
21060
S92
P
G
G
V
E
F
P
S
G
F
R
S
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61657
175
19275
S67
P
S
G
V
D
Y
P
S
G
F
Q
G
G
L
R
Rat
Rattus norvegicus
Q04667
175
19118
S67
P
S
G
V
D
Y
P
S
G
F
R
G
G
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511924
287
29320
T104
S
E
C
M
N
E
V
T
R
F
L
S
T
C
E
Chicken
Gallus gallus
O57337
290
31053
N120
A
G
F
N
E
C
M
N
E
V
T
R
F
L
S
Frog
Xenopus laevis
Q8AVU4
267
28644
T122
S
E
C
M
N
E
V
T
R
F
L
S
T
C
E
Zebra Danio
Brachydanio rerio
Q9I9L0
324
34311
T131
I
G
F
R
E
C
L
T
E
V
A
R
Y
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26263
435
46532
E125
T
G
F
V
E
C
A
E
E
V
N
R
Y
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175739
383
41428
D216
M
T
S
L
Q
P
P
D
A
A
A
P
R
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28
N.A.
67
N.A.
65.5
63.9
N.A.
25.7
24.1
25.8
22.5
N.A.
20.9
N.A.
N.A.
21.9
Protein Similarity:
100
39.7
N.A.
70
N.A.
70.4
72
N.A.
35.8
36.2
35.9
33.3
N.A.
29.6
N.A.
N.A.
31.3
P-Site Identity:
100
20
N.A.
6.6
N.A.
13.3
13.3
N.A.
20
6.6
20
6.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
46.6
N.A.
13.3
N.A.
20
20
N.A.
46.6
33.3
46.6
33.3
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
10
10
19
0
0
0
0
% A
% Cys:
0
0
37
0
0
28
0
0
0
0
0
0
0
28
0
% C
% Asp:
0
0
0
0
19
0
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
28
0
0
37
28
0
10
28
0
0
0
0
0
28
% E
% Phe:
0
0
28
0
0
10
0
0
0
55
0
0
10
0
0
% F
% Gly:
0
37
28
0
0
10
0
0
28
0
0
19
28
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
19
0
0
10
0
0
10
37
0
0
55
0
% L
% Met:
10
0
0
28
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
28
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
28
0
0
0
10
10
37
0
0
0
0
10
0
0
19
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
28
0
19
37
19
0
10
% R
% Ser:
28
28
10
0
0
0
0
37
0
0
0
37
0
0
28
% S
% Thr:
10
10
0
0
0
0
0
37
0
0
10
0
28
0
0
% T
% Val:
0
0
0
37
0
0
37
0
0
28
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
0
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _